超音波検査技術

ISSN: 1881-4506
一般社団法人日本超音波検査学会
〒162-0801 東京都新宿区山吹町358-5
Japanese Journal of Medical Ultrasound Technology 50(2): 137-146 (2025)
doi:10.11272/jss.436

症例報告Case Report

経胸壁心エコー図検査によって溶血性貧血の原因が上行大動脈人工血管中枢吻合部-右室流出路仮性瘤穿破と示唆された1症例A Case of Hemolytic Anemia Caused by Perforation of the Ascending Aortic Graft Central Anastomosis-right Ventricular Outflow Tract Pseudoaneurysm, Identified by Echocardiography

1国立病院機構九州医療センター臨床検査部Department of Clinical Laboratory Medicine, National Hospital Organization Kyushu Medical Center

2国立病院機構福岡東医療センター臨床検査科Department of Clinical Laboratory Medicine, Fukuoka Higashi Medical Center, National Hospital Organization

受付日:2024年6月3日Received: June 3, 2024
受理日:2025年1月24日Accepted: January 24, 2025
発行日:2025年4月1日Published: April 1, 2025
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症例は80代女性,202X–10年にStanford A型大動脈解離を発症し,上行大動脈置換術を施行.他院でフォローされていたが,溶血性貧血を認め,今回術後のフォローも含む目的にて受診した.来院時の聴診では連続性雑音を聴取した.経胸壁心エコー図検査では,傍胸骨左室長軸断面より上行大動脈人工血管中枢吻合部にCavityを認め,仮性瘤が疑われた.カラードプラ法では上行大動脈人工血管中枢吻合部から仮性瘤内に収縮期,拡張期ともに連続性に流入するカラーシグナルを認めた.連続波ドプラ法では仮性瘤内へと流入する血流は拍動性の連続性波形を呈していた.また,仮性瘤内から右室流出路側に流出していくカラーシグナルを認め,連続波ドプラ法では右室流出路へと流入する血流は拍動性の連続性波形であった.大動脈弁短軸レベル断面でも右室流出路を描出しカラードプラ法で確認すると右室流出路に流出する血流を認めた.経胸壁心エコー図検査から上行大動脈人工血管中枢吻合部から右室流出路仮性瘤への穿破が疑われた.溶血性貧血の原因として自己免疫性や発作性夜間ヘモグロビン尿症は否定的であり,造影CT検査においても上行大動脈人工血管の内腔に高度狭窄は認められなかったことから,上行大動脈人工血管吻合部から右室流出路仮性瘤への穿破による機械的溶血による溶血性貧血の原因であると考えられた.

A female patient in her 80s developed Stanford type A aortic dissection in 202X–10 and underwent ascending aortic replacement. She had been followed up at another hospital; however, because she was diagnosed with hemolytic anemia, she was observed for postoperative follow-up. On admission, continuous murmur was audible. Transthoracic echocardiography revealed a cavity at the central anastomosis of the ascending aortic graft in the parasternal left ventricular long-axis section, and a pseudoaneurysm was suspected. Color Doppler imaging revealed a continuous color signal flowing into the pseudoaneurysm from the central anastomosis of the ascending aortic graft during both systole and diastole. Continuous-wave Doppler imaging demonstrated that the blood flow into the pseudoaneurysm had a pulsatile continuous waveform. Furthermore, a color signal flowing from the pseudoaneurysm to the right ventricular outflow tract was detected, and continuous-wave Doppler imaging revealed a pulsatile continuous waveform of the blood flowing into the right ventricular outflow tract. The right ventricular outflow tract was also visualized in a section at the level of the short axis of the aortic valve, and the blood flow into the right ventricular outflow tract was confirmed by color Doppler imaging. Transthoracic echocardiography indicated perforation from the central anastomosis of the ascending aorta to the right ventricular outflow tract pseudoaneurysm. Autoimmunity and paroxysmal nocturnal hemoglobinuria were eliminated as the cause of hemolytic anemia, and no severe stenosis was detected in the lumen of the ascending aortic graft on contrast-enhanced CT. The cause of hemolytic anemia was mechanical hemolysis due to perforation of the right ventricular outflow tract pseudoaneurysm.

Key words: perforation; pseudoaneurysm; hemolytic anemia; ultrasonography

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